![]() 5, 6 The role of antipsychotic maintenance medication in symptom control and the prevention of relapse of schizophrenia is well established. ![]() In the acute phase, the patient routinely experiences psychotic symptoms, with pharmacotherapy being initiated or adjusted as soon as possible. Treatment of schizophrenia is typically divided into three phases: acute, stabilization, and maintenance. 1 TAPs are associated with an increased incidence of adverse events (AEs) known as extrapyramidal symptoms (EPS) 1 however, AAPs are associated with an increased risk of weight gain and metabolic AEs. AAPs appear to be more effective in the treatment of negative symptoms. Both classes are considered equally effective in the treatment of positive symptoms. 2, 4 Existing antipsychotic therapies fall into one of two classes: typical antipsychotics (TAP) and atypical antipsychotics (AAP). 3 Antipsychotic medications form the cornerstone of treatment for schizophrenia. 1 In Canada, the disease affects about 1% of the population, 2 or about 234,000 people (2004 data). 1, 2 Patients with schizophrenia are at an increased risk for numerous other medical illnesses, including suicide. Schizophrenia is a chronic mental illness that requires lifelong treatment.
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